Bcl-2 (BH3 Domain Specific) Antibody
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Catalogue No: abx027164
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US$326.25
(Size: 80 µl)
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Datasheet SDS
BCL2 is integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.
Research Articles on Bcl-2 (BH3 Domain Specific)
| Target | Bcl-2 (BH3 Domain Specific) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/100, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 75-110 amino acids from human Bcl. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P10415 (UniProt, ExPASy) |
| UniProt Secondary AC | C9JHD5, P10416, Q13842, Q16197 |
| UniProt Entry Name | BCL2_HUMAN |
| NCBI Accession | NP_000624.2 |
| KEGG | hsa:596 |
| String | 9606.ENSP00000381185 |
| Molecular Weight | Calculated MW: 26.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow BCL2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |