Apoptosis Regulator Bcl-2 (BCL2) Antibody
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Catalogue No: abx031231
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].
Research Articles on Apoptosis Regulator Bcl-2 (BCL2)
| Target | Apoptosis Regulator Bcl-2 (BCL2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 87-116 amino acids from the Central region of human BCL2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P10415 (UniProt, ExPASy) |
| UniProt Secondary AC | C9JHD5, P10416, Q13842, Q16197 |
| UniProt Entry Name | BCL2_HUMAN |
| Gene Symbol | BCL2 |
| GeneID | 596 |
| OMIM | 151430 |
| HGNC | 990 |
| KEGG | hsa:596 |
| Ensembl | ENSG00000171791 |
| String | 9606.ENSP00000381185 |
| Molecular Weight | Calculated MW: 26.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Hamster BCL2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |