3(2),5-Bisphosphate Nucleotidase 1 (BPNT1) Antibody
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Catalogue No: abx028884
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US$326.25
(Size: 80 µl)
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Datasheet SDS
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Research Articles on 3(2),5-Bisphosphate Nucleotidase 1 (BPNT1)
| Target | 3(2),5-Bisphosphate Nucleotidase 1 (BPNT1) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of human BPNT1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O95861 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7C8, B4DPS5, B4DUS9, D3DTA9, Q8WVL5, Q9UGJ3 |
| UniProt Entry Name | BPNT1_HUMAN |
| Gene Symbol | BPNT1 |
| KEGG | hsa:10380 |
| String | 9606.ENSP00000446828 |
| Molecular Weight | Calculated MW: 33.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |