Carfilzomib
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Price:
US$137.75
(Size: 5 mg)
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Carfilzomib (PR-171) is an irreversible proteasome inhibitor that targets the chymotrypsin-like beta5 subunit of 20S proteasome. It can arrest the cell cycle and trigger apoptosis in tumor cell lines. It is provided as a white powder.
This product acts on the following target types: Proteasome.
This product acts on the following biochemical pathways: Degradation, Cell cycle, Apoptosis inducer, Cytotoxicity.
This product may be of interest in the following research areas and diseases: Ubiquitin/Proteasome, Cell death, Cancer.
This product may act as a Coronavirus inhibitor: Inhibits SARS-CoV in silico, probably through blocking the main protease, Mpro (3CLpro, Nsp5).
Please note that our chemical products are for scientific research use only and are not for medical or veterinary use. This product can only be dispatched to a scientific business or laboratory address.
Target |
Carfilzomib |
Form |
Solid |
Purity |
> 98% (HPLC). Conforms to structure by NMR. |
Reconstitution |
Soluble in DMSO (up to 80 mg/ml) or in Ethanol (up to 25 mg/ml). |
Storage |
Store desiccated at -20 °C for up to 1 year. Solutions can be stored at -20 °C for up to 1 week. |
Molecular Weight |
719.9 g/mol |
Molecular Formula |
C40H57N5O7 |
Buffer |
Not applicable. |
CAS Number |
868540-17-4 |
SMILES |
O=C([C@]1(C)OC1)[C@H](CC(C)C)NC([C@@H](NC([C@@H](NC([C@H](CCC2=CC=CC=C2)NC(CN3CCOCC3)=O)=O)CC(C)C)=O)CC4=CC=CC=C4)=O |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Research Articles on Carfilzomib