Carfilzomib

Carfilzomib (PR-171) is an irreversible proteasome inhibitor that targets the chymotrypsin-like beta5 subunit of 20S proteasome. It can arrest the cell cycle and trigger apoptosis in tumor cell lines. It is provided as a white powder.

This product acts on the following target types: Proteasome.
This product acts on the following biochemical pathways: Degradation, Cell cycle, Apoptosis inducer, Cytotoxicity.
This product may be of interest in the following research areas and diseases: Ubiquitin/Proteasome, Cell death, Cancer.
This product may act as a Coronavirus inhibitor: Inhibits SARS-CoV in silico, probably through blocking the main protease, Mpro (3CLpro, Nsp5).

Please note that our chemical products are for scientific research use only in a laboratory and are not for medical or veterinary use. This product can only be dispatched to a scientific business or laboratory address.

Target	Carfilzomib
Form	Solid
Purity	> 98% (HPLC). Conforms to structure by NMR.
Reconstitution	Soluble in DMSO (up to 80 mg/ml) or in Ethanol (up to 25 mg/ml).
Storage	Store desiccated at -20°C. Solutions can be stored at -20°C for up to 1 week.
Shelf Life	Up to 12 months.
Molecular Weight	719.9 g/mol
Molecular Formula	C40H57N5O7
Buffer	Not applicable.
CAS Number	868540-17-4
SMILES	O=C([C@]1(C)OC1)[C@H](CC(C)C)NC([C@@H](NC([C@@H](NC([C@H](CCC2=CC=CC=C2)NC(CN3CCOCC3)=O)=O)CC(C)C)=O)CC4=CC=CC=C4)=O
Availability	Shipped within 5-10 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Carfilzomib

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