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Endoglin / CD105 (ENG) Antibody
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Catalogue No: abx011982
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US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
Research Articles on Endoglin / CD105 (ENG)
| Target | Endoglin / CD105 (ENG) |
| Research Area | Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD105 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P17813 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14248, Q14926, Q5T9C0 |
| UniProt Entry Name | EGLN_HUMAN |
| Gene Symbol | ENG |
| GeneID | 2022 |
| OMIM | 131195 |
| HGNC | 3349 |
| KEGG | hsa:2022 |
| Ensembl | ENSG00000106991 |
| String | 9606.ENSP00000362299 |
| Molecular Weight | 71 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |