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| Target | Endoglin / CD105 (ENG) |
| Research Area | Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Monoclonal |
| Clone | J635 |
| Reactivity | Human, Rat |
| Tested Applications | FCM |
| Host | Mouse |
| Recommended dilutions | FCM: 10 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | APC |
| Excitation/Emission | 651/660 |
| Laser Line | 647 |
| Immunogen | Recombinant Vaccinia virus containing the Human CD105 cDNA. |
| Isotype | IgG2a |
| Form | Liquid |
| Storage | Store in the dark at 2°C to 8°C. Avoid exposure to light. Do not freeze. |
| Shelf Life | The shelf life is at least 24 months. |
| UniProt Primary AC | P17813 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14248, Q14926, Q5T9C0 |
| UniProt Entry Name | EGLN_HUMAN |
| Gene Symbol | ENG |
| GeneID | 2022 |
| OMIM | 131195 |
| HGNC | 3349 |
| KEGG | hsa:2022 |
| Ensembl | ENSG00000106991 |
| String | 9606.ENSP00000362299 |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Specificity | The antibody reacts with CD105 (Endoglin), a 90 kDa type I homodimerizing membrane glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow; it is also present on syncytiotrophoblast on placenta throughout pregnancy. |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |