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| Target | Integrin Beta 2 (ITGB2) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Tumor Immunity, Cancer |
| Clonality | Monoclonal |
| Clone | F231 |
| Reactivity | Human |
| Tested Applications | WB, FCM |
| Host | Mouse |
| Recommended dilutions | WB: 1-2 µg/ml, FCM: 1-5 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Peripheral blood mononuclear cells. |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | > 95% (SDS-PAGE) 0.2 µm sterile filtered |
| Purification | Purified by Protein A affinity chromatography. |
| Storage | Store at 2-8°C. Do not freeze. |
| Shelf Life | The shelf life is at least 24 months. |
| UniProt Primary AC | P05107 (UniProt, ExPASy) |
| Gene Symbol | ITGB2 |
| GeneID | 3689 |
| KEGG | hsa:3689 |
| String | 9606.ENSP00000380948 |
| Buffer | Low endotoxin PBS. This product does not contain azides. |
| Endotoxin Level | Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test. |
| Specificity | The antibody recognizes an epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18. CD18 (integrin beta2 subunit; beta2 integrin) is a 90-95 kDa type I transmembrane protein expressed on all leukocytes. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |