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| Target | Hematopoietic Progenitor Cell Antigen CD34 (CD34) |
| Research Area | Cellular Differentiation and Adhesion, Developmental Science, Genetics |
| Clonality | Monoclonal |
| Clone | E334 |
| Reactivity | Human |
| Tested Applications | FCM |
| Host | Mouse |
| Recommended dilutions | FCM: 10 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | APC |
| Excitation/Emission | 651/660 |
| Laser Line | 647 |
| Immunogen | Permanent Human cell line derived from peripheral leucocytes of a patient suffering from chronic myeloid leukaemia. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified by size-exclusion chromatography. |
| Storage | Store in the dark at 2°C to 8°C. Avoid exposure to light. Do not freeze. |
| Shelf Life | The shelf life is at least 12 months. |
| UniProt Primary AC | P28906 (UniProt, ExPASy) |
| Gene Symbol | CD34 |
| GeneID | 947 |
| KEGG | hsa:947 |
| String | 9606.ENSP00000310036 |
| Buffer | Stabilizing PBS, pH 7.4, containing 15 mM sodium azide. |
| Specificity | The antibody reacts with Class III epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells. It is gradually lost on progenitor cells. This antibody completely blocks binding of Class II antibody QBEnd10 and Class III antibodies BIRMA K3 and 8G12 on KG1a cell line. |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |