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| Target | Hematopoietic Progenitor Cell Antigen CD34 (CD34) |
| Research Area | Cellular Differentiation and Adhesion, Developmental Science, Genetics |
| Clonality | Monoclonal |
| Clone | E334 |
| Reactivity | Human |
| Tested Applications | FCM |
| Host | Mouse |
| Recommended dilutions | FCM: 20 µl/100 µl of whole blood or 106 cells. Tested in IHC-P and ICC. Optimal dilutions/concentrations should be determined by the end user. The content of a vial (2 ml) is sufficient for 100 tests. |
| Conjugation | FITC |
| Excitation/Emission | 499/515 |
| Laser Line | 488 |
| Immunogen | Permanent Human cell line derived from peripheral leucocytes of a patient suffering from chronic myeloid leukaemia. |
| Isotype | IgG1 |
| Form | Liquid |
| Storage | Store in the dark at 2°C to 8°C. Avoid exposure to light. Do not freeze. |
| Shelf Life | The shelf life is at least 12 months. |
| UniProt Primary AC | P28906 (UniProt, ExPASy) |
| Gene Symbol | CD34 |
| GeneID | 947 |
| KEGG | hsa:947 |
| String | 9606.ENSP00000310036 |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Specificity | The antibody reacts with Class III epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells; it is gradually lost on progenitor cells. The antibody 4H11[APG] completely blocks binding of Class II antibody QBEnd10 and Class III antibodies BIRMA K3 and 8G12 on KG1a cell line. |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |