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T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) Antibody
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Catalogue No: abx027825
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
T-cell receptor zeta, together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, delta and epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response.
Research Articles on T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247)
| Target | T-Cell Surface Glycoprotein CD3 Zeta Chain (CD247) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/4000 - 1/8000, FCM: 1/25. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 113-141 amino acids from the C-terminal region of human CD3Z. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P20963 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AK49, Q5VX13, Q8TAX4 |
| Gene Symbol | CD3Z |
| Molecular Weight | Calculated MW: 18.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Pig CD247. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |