Natural Killer Cells Antigen CD94 (KLRD1) Antibody
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Catalogue No: abx011233
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Tissue specificity: Natural killer cells.
Research Articles on Natural Killer Cells Antigen CD94 (KLRD1)
| Target | Natural Killer Cells Antigen CD94 (KLRD1) |
| Research Area | Signal Transduction, Cellular Differentiation and Adhesion, Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD94 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q13241 (UniProt, ExPASy) |
| UniProt Secondary AC | O43321, O43773, Q9UBE3, Q9UEQ0 |
| UniProt Entry Name | KLRD1_HUMAN |
| Gene Symbol | KLRD1 |
| GeneID | 3824 |
| OMIM | 602894 |
| HGNC | 6378 |
| KEGG | hsa:3824 |
| Ensembl | ENSG00000134539 |
| String | 9606.ENSP00000371333 |
| Molecular Weight | 21 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |