Cyclin-Dependent Kinase 1 (CDK1) Antibody
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Catalogue No: abx028464
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US$326.25
(Size: 80 µl)
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Datasheet SDS
CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of CDC2 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Research Articles on Cyclin-Dependent Kinase 1 (CDK1)
| Target | Cyclin-Dependent Kinase 1 (CDK1) |
| Research Area | Signal Transduction, Enzymes and Kinases, Tumor Immunity, Neuroscience, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 213-241 amino acids from the C-terminal region of human CDC2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P06493 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7C4, C9J497, O60764 |
| UniProt Entry Name | CDK1_HUMAN |
| KEGG | hsa:983 |
| String | 9606.ENSP00000378699 |
| Molecular Weight | Calculated MW: 34.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Xenopus CDK1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |