Cyclin Dependent Kinase 1 Phospho-Tyr15 (CDK1 pY15) Antibody
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Catalogue No: abx000105
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US$232.00
(Size: 20 µl)
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Datasheet SDS
CDK1 (pY15) Antibody is a Rabbit Polyclonal antibody against CDK1 (pY15). The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Cyclin Dependent Kinase 1 Phospho-Tyr15 (CDK1 pY15)
| Target | Cyclin Dependent Kinase 1 Phospho-Tyr15 (CDK1 pY15) |
| Clonality | Polyclonal |
| Target Modification | Tyr15 |
| Modification | Phosphorylation |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to CDK1 pY15. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P06493 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K7C4, C9J497, O60764 |
| UniProt Entry Name | CDK1_HUMAN |
| Gene Symbol | CDK1 |
| GeneID | 983 |
| NCBI Accession | NP_001777.1 |
| KEGG | hsa:983 |
| String | 9606.ENSP00000378699 |
| Molecular Weight | Calculated MW: 34 kDa Observed MW: 34 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |