Cyclin-Dependent Kinase 14 (Cdk14) Antibody
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Catalogue No: abx031006
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity).
Research Articles on Cyclin-Dependent Kinase 14 (Cdk14)
| Target | Cyclin-Dependent Kinase 14 (Cdk14) |
| Research Area | Developmental Science |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 45-72 amino acids from the N-terminal region of mouse Cdk14. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O35495 (UniProt, ExPASy) |
| UniProt Secondary AC | O35848, Q3TNN9, Q3V319, Q6ZQ37 |
| UniProt Entry Name | CDK14_MOUSE |
| KEGG | mmu:18647 |
| String | 10090.ENSMUSP00000030763 |
| Molecular Weight | Calculated MW: 53 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |