CCAAT/Enhancer Binding Protein Alpha (CEBPA) Antibody
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Catalogue No: abx034388
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
C/EBP alpha is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. This protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Research Articles on CCAAT/Enhancer Binding Protein Alpha (CEBPA)
| Target | CCAAT/Enhancer Binding Protein Alpha (CEBPA) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 304-330 amino acids from the C-terminal region of human CEBPA. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P49715 (UniProt, ExPASy) |
| UniProt Secondary AC | A7LNP2, P78319, Q05CA4 |
| UniProt Entry Name | CEBPA_HUMAN |
| KEGG | hsa:1050 |
| String | 9606.ENSP00000427514 |
| Molecular Weight | Calculated MW: 37.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat and Cow CEBPA. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |