Chitinase 1 (CHIT1) Antibody
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Catalogue No: abx015729
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
CHIT1:chitinase 1 (chitotriosidase).Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18.It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients.The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture.Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression.This enzyme may play a role in the degradation of chitin-containing pathogens.
Research Articles on Chitinase 1 (CHIT1)
| Target | Chitinase 1 (CHIT1) |
| Research Area | Enzymes and Kinases |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q13231 (UniProt, ExPASy) |
| UniProt Entry Name | CHIT1_HUMAN |
| Gene Symbol | CHIT1 |
| GeneID | 1118 |
| OMIM | 600031 |
| HGNC | 1936 |
| KEGG | hsa:1118 |
| Ensembl | ENSG00000133063 |
| String | 9606.ENSP00000356198 |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |