Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1) Antibody (Detection Ab)
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Catalogue No: abx019246
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US$319.00
(Size: 100 µg)
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Datasheet SDS
Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1), also known as Keratin, type I cytoskeletal 19, cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. Serum CYFRA 21-1 (cytokeratin-19 fragments) may be a reliable marker of recurrence or therapeutic efficacy, and has been used for monitoring the recurrence of breast cancer and in evaluating therapeutic effects. Serum CYFRA 21-1 has also been used as a biomarker for diagnosis of nonsmall cell lung cancer (NSCLC), and has ben reported to be elevated in nasopharyngeal carcinoma (NPC). It can function as a biomarker for detection and monitoring of NPC. CYFRA21-1/CK19 (Capture Ab) is a Mouse Monoclonal antibody against Human CYFRA21-1/CK19. For ELISA and CLIA immunoassays, it is recommended to use abx019245 as the capture antibody and abx019246 (this product) as the detection antibody.
Research Articles on Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1)
| Target | Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1) |
| Clonality | Monoclonal |
| Clone | T293 |
| Reactivity | Human |
| Tested Applications | ELISA, WB, CLIA |
| Host | Mouse |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | 40 kDa of Keratin 19 protein. |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | > 95% (HPLC and SDS-PAGE) |
| Purification | Purified by Protein A or Protein G. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P08727 (UniProt, ExPASy) |
| GeneID | 3880 |
| OMIM | 148020 |
| Buffer | 0.01 M PBS, pH 7.4 containing 0.15 M NaCl. Does not contain preservatives. |
| Specificity | Recognizes human CK19 / CYFRA21-1. May cross-react with CK20, CK8 and CK18. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |