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Complement C3 (C3) Antibody (FITC)
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Catalogue No: abx106700
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US$188.50
(Size: 20 µg)
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Datasheet SDS
Complement C3 (C3) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC against Complement C3. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Research Articles on Complement C3 (C3)
| Target | Complement C3 (C3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Host | Rabbit |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | FITC |
| Excitation/Emission | 499/515 |
| Laser Line | 488 |
| Immunogen | Recombinant human Complement C3 protein (26-225AA). |
| Isotype | IgG |
| Form | Liquid |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P01024 (UniProt, ExPASy) |
| UniProt Secondary AC | A7E236 |
| UniProt Entry Name | CO3_HUMAN |
| Gene Symbol | C3 |
| GeneID | 718 |
| OMIM | 120700 |
| HGNC | 1318 |
| KEGG | hsa:718 |
| Ensembl | ENSG00000125730 |
| String | 9606.ENSP00000245907 |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Concentration | 0.25 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |