Carbamoyl Phosphate Synthase 1, Mitochondrial (CPS1) Antibody
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Catalogue No: abx028561
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
Research Articles on Carbamoyl Phosphate Synthase 1, Mitochondrial (CPS1)
| Target | Carbamoyl Phosphate Synthase 1, Mitochondrial (CPS1) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 262-291 amino acids from the N-terminal region of human CPS1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P31327 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z818, J3KQL0, O43774, Q53TL5, Q59HF8, Q7Z5I5 |
| UniProt Entry Name | CPSM_HUMAN |
| Gene Symbol | CPS1 |
| KEGG | hsa:1373 |
| String | 9606.ENSP00000402608 |
| Molecular Weight | Calculated MW: 165 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |