Cyclic AMP-Responsive Element Binding Protein 3 (CREB3) Antibody
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Catalogue No: abx031346
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.
Research Articles on Cyclic AMP-Responsive Element Binding Protein 3 (CREB3)
| Target | Cyclic AMP-Responsive Element Binding Protein 3 (CREB3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CREB3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O43889 (UniProt, ExPASy) |
| UniProt Secondary AC | D0PTW6, O14671, O14919, Q5TCV1, Q96GK8, Q9H2W3, Q9UE77 |
| UniProt Entry Name | CREB3_HUMAN |
| Gene Symbol | CREB3 |
| KEGG | hsa:10488 |
| String | 9606.ENSP00000342136 |
| Molecular Weight | Calculated MW: 41.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |

