Cytochrome P450 1A1 (CYP1A1) Antibody
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Catalogue No: abx001771
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US$217.50
(Size: 20 µl)
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Datasheet SDS
CYP1A1 Antibody is a Rabbit Polyclonal antibody against CYP1A1. This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008].
Research Articles on Cytochrome P450 1A1 (CYP1A1)
| Target | Cytochrome P450 1A1 (CYP1A1) |
| Research Area | Metabolism |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to CYP1A1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P04798 (UniProt, ExPASy) |
| UniProt Secondary AC | A4F3V9, A4F3W0, Q53G18 |
| UniProt Entry Name | CP1A1_HUMAN |
| Gene Symbol | CYP1A1 |
| GeneID | 1543 |
| NCBI Accession | NP_000490.1 |
| KEGG | hsa:1543 |
| String | 9606.ENSP00000369050 |
| Molecular Weight | Calculated MW: 58 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |