24-Dehydrocholesterol Reductase (DHCR24) Antibody
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Catalogue No: abx004137
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US$217.50
(Size: 20 µl)
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Datasheet SDS
DHCR24 Antibody is a Rabbit Polyclonal antibody against DHCR24. This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Research Articles on 24-Dehydrocholesterol Reductase (DHCR24)
| Target | 24-Dehydrocholesterol Reductase (DHCR24) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to DHCR24. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q15392 (UniProt, ExPASy) |
| UniProt Secondary AC | B7Z817, D3DQ51, Q9HBA8 |
| UniProt Entry Name | DHC24_HUMAN |
| Gene Symbol | DHCR24 |
| GeneID | 1718 |
| NCBI Accession | NP_055577.1 |
| KEGG | hsa:1718 |
| String | 9606.ENSP00000360316 |
| Molecular Weight | Calculated MW: 60 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1.27 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |