EPH Receptor A1 (EphA1) Antibody
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Catalogue No: abx010718
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US$427.75
(Size: 100 µl)
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Datasheet SDS
EPH receptor A1 (EphA1), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.
Research Articles on EPH Receptor A1 (EphA1)
| Target | EPH Receptor A1 (EphA1) |
| Research Area | Tumor Immunity, Neuroscience, Developmental Science, Hepatology, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of EphA1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P21709 (UniProt, ExPASy) |
| UniProt Secondary AC | A1L3V3, B5A966, B5A967, Q15405 |
| UniProt Entry Name | EPHA1_HUMAN |
| Gene Symbol | EPHA1 |
| GeneID | 2041 |
| OMIM | 179610 |
| HGNC | 3385 |
| KEGG | hsa:2041 |
| Ensembl | ENSG00000146904 |
| String | 9606.ENSP00000275815 |
| Enzyme Commission Number | EC 2.7.10.1 |
| Molecular Weight | 108 kDa |
| Buffer | PBS, containing 0.03% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |