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Receptor Tyrosine-Protein Kinase ErbB-4 (ERBB4) Antibody
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Catalogue No: abx033548
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Research Articles on Receptor Tyrosine-Protein Kinase ErbB-4 (ERBB4)
| Target | Receptor Tyrosine-Protein Kinase ErbB-4 (ERBB4) |
| Research Area | Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 25-55 amino acids from the N-terminal region of human ERBB4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q15303 (UniProt, ExPASy) |
| UniProt Secondary AC | B7ZLD7, B7ZLE2, B7ZLE3, Q2M1W1, Q59EW4 |
| UniProt Entry Name | ERBB4_HUMAN |
| NCBI Accession | NP_001036064.1 NP_005226.1 |
| KEGG | hsa:2066 |
| String | 9606.ENSP00000342235 |
| Molecular Weight | Calculated MW: 147 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat ERBB4. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |