DNA Excision Repair Protein ERCC-8 (ERCC8) Antibody
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Catalogue No: abx026010
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
Research Articles on DNA Excision Repair Protein ERCC-8 (ERCC8)
| Target | DNA Excision Repair Protein ERCC-8 (ERCC8) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 210-238 amino acids from the Central region of human ERCC8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q13216 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RB64, Q6FHX5, Q96GB9 |
| UniProt Entry Name | ERCC8_HUMAN |
| Gene Symbol | ERCC8 |
| GeneID | 1161 |
| HGNC | 3439 |
| KEGG | hsa:1161 |
| String | 9606.ENSP00000265038 |
| Molecular Weight | Calculated MW: 44.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |