Estrogen Receptor (ESR1) Antibody
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Catalogue No: abx015850
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US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription.The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2.Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone.Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Research Articles on Estrogen Receptor (ESR1)
| Target | Estrogen Receptor (ESR1) |
| Research Area | Endocrinology |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human ESR1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P03372 (UniProt, ExPASy) |
| UniProt Secondary AC | Q13511, Q14276, Q5T5H7, Q6MZQ9, Q9NU51, Q9UDZ7, Q9UIS7 |
| UniProt Entry Name | ESR1_HUMAN |
| Gene Symbol | ESR1 |
| GeneID | 2099 |
| OMIM | 133430 |
| HGNC | 3467 |
| KEGG | hsa:2099 |
| Ensembl | ENSG00000091831 |
| String | 9606.ENSP00000405330 |
| Molecular Weight | 66 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |