+44 (0) 1223 755950
+1 832 327 7413
Orders to United States ship from United States
| Target | Major Histocompatibility Complex Class I E (HLA-E) |
| Research Area | Signal Transduction, Tumor Immunity, Infection Immunity, Immunology, Developmental Science, Cancer |
| Clonality | Monoclonal |
| Clone | Q331 |
| Reactivity | Human |
| Tested Applications | IHC, FCM, IP |
| Host | Mouse |
| Recommended dilutions | IHC-P: 10 μg/ml, FCM: 1-4 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide. |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by protein A affinity chromatography followed by size-exclusion chromatography. |
| Storage | Store at 2-8°C. Do not freeze. |
| Shelf Life | The shelf life is at least 24 months. |
| UniProt Primary AC | P13747 (UniProt, ExPASy) |
| Gene Symbol | HLA-E |
| GeneID | 3133 |
| KEGG | hsa:3133 |
| String | 9606.ENSP00000365817 |
| Buffer | PBS, containing 15 mM sodium azide. |
| Specificity | The antibody recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results revealed that the antibody cross-reacts with some classical MHC Class I molecules (MHC Class Ia): HLA-B7 (strongly), HLA-B8 (moderately), HLA-B27, -B44 (weakly). |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |