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Peptidyl-tRNA Hydrolase ICT1, Mitochondrial (ICT1) Antibody
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Catalogue No: abx034725
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US$326.25
(Size: 80 µl)
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Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.
Research Articles on Peptidyl-tRNA Hydrolase ICT1, Mitochondrial (ICT1)
| Target | Peptidyl-tRNA Hydrolase ICT1, Mitochondrial (ICT1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 153-179 amino acids from the C-terminal region of human ICT1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14197 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RAD1, Q53HM7, Q53Y11 |
| UniProt Entry Name | ICT1_HUMAN |
| NCBI Accession | NP_001536.1 |
| KEGG | hsa:3396 |
| String | 9606.ENSP00000301585 |
| Molecular Weight | Calculated MW: 23.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |