Inhibin Beta A (INHBA) Antibody
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Catalogue No: abx004475
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US$217.50
(Size: 20 µl)
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Datasheet SDS
Inhibin Beta A (INHBA) Antibody is a Rabbit Polyclonal antibody against INHBA. The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
Research Articles on Inhibin Beta A (INHBA)
| Target | Inhibin Beta A (INHBA) |
| Research Area | Tumor Immunity, Endocrinology, Reproductive Science, Hormone Metabolism, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 21-426 of human Inhibin beta A (INHBA). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P08476 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14599 |
| UniProt Entry Name | INHBA_HUMAN |
| Gene Symbol | INHBA |
| GeneID | 3624 |
| NCBI Accession | NP_002183.1 |
| KEGG | hsa:3624 |
| String | 9606.ENSP00000242208 |
| Molecular Weight | Calculated MW: 47 kDa Observed MW: 47 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 0.627 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |