Potassium Intermediate Small Conductance Calcium Activated Channel Subfamily N, Member 1 (KCNN1) Antibody
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Catalogue No: abx029367
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(Size: 80 µl)
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Datasheet SDS
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes.
Research Articles on Potassium Intermediate Small Conductance Calcium Activated Channel Subfamily N, Member 1 (KCNN1)
| Target | Potassium Intermediate Small Conductance Calcium Activated Channel Subfamily N, Member 1 (KCNN1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 391-419 amino acids from the C-terminal region of human KCNN1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q92952 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5KR10, Q6DJU4 |
| UniProt Entry Name | KCNN1_HUMAN |
| KEGG | hsa:3780 |
| String | 9606.ENSP00000476519 |
| Molecular Weight | Calculated MW: 60 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |