Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody
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Catalogue No: abx025535
Price:
US$623.50
(Size: 100 µl)
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Datasheet SDS
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. This antibody is supplied as crude ascites.
Research Articles on Lymphoid Enhancer Binding Factor 1 (LEF1)
| Target | Lymphoid Enhancer Binding Factor 1 (LEF1) |
| Research Area | Tumor Immunity, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/8000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 10-37 amino acids from human LEF1. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9UJU2 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DG38, B7Z8E2, E9PDK3, Q3ZCU4, Q9HAZ0 |
| UniProt Entry Name | LEF1_HUMAN |
| String | 9606.ENSP00000265165 |
| Molecular Weight | Calculated MW: 44.2 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat LEF1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |