Mitogen-Activated Protein Kinase 1 / ERK2 (MAPK1) Antibody
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Catalogue No: abx033263
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
MAPK1 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.
Research Articles on Mitogen-Activated Protein Kinase 1 / ERK2 (MAPK1)
| Target | Mitogen-Activated Protein Kinase 1 / ERK2 (MAPK1) |
| Research Area | Signal Transduction, Enzymes and Kinases, Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 316-345 amino acids from the C-terminal region of human MAPK1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P28482 (UniProt, ExPASy) |
| UniProt Secondary AC | A8CZ64 |
| UniProt Entry Name | MK01_HUMAN |
| NCBI Accession | NP_002736.3 NP_620407.1 |
| KEGG | hsa:5594 |
| String | 9606.ENSP00000215832 |
| Molecular Weight | Calculated MW: 41.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow MAPK1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |