Mitogen-Activated Protein Kinase 11 (MAPK11) Antibody
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Catalogue No: abx011781
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase. Alternatively spliced transcript variants encoding the same protein have been observed.
Research Articles on Mitogen-Activated Protein Kinase 11 (MAPK11)
| Target | Mitogen-Activated Protein Kinase 11 (MAPK11) |
| Research Area | Signal Transduction, Enzymes and Kinases, Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of MAPK11 (aa251-363) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q15759 (UniProt, ExPASy) |
| UniProt Entry Name | MK11_HUMAN |
| Gene Symbol | MAPK11 |
| GeneID | 5600 |
| OMIM | 602898 |
| HGNC | 6873 |
| KEGG | hsa:5600 |
| Ensembl | ENSG00000185386 |
| String | 9606.ENSP00000333685 |
| Enzyme Commission Number | EC 2.7.11.24 EC 2.7.1.37 |
| Molecular Weight | 42 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |