Nuclear Factor Erythroid 2-Related Factor 1 (NFE2L1) Antibody
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Catalogue No: abx004247
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US$217.50
(Size: 20 µl)
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Datasheet SDS
NFE2L1 Antibody is a Rabbit Polyclonal antibody against NFE2L1. This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NFE2L1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1.
Research Articles on Nuclear Factor Erythroid 2-Related Factor 1 (NFE2L1)
| Target | Nuclear Factor Erythroid 2-Related Factor 1 (NFE2L1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, ChIP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, ChIP: 5 µg antibody per 10 µg - 15 µg of Chromatin. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 240-449 of human NRF1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q16656 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K4C6, B4DDV6, Q15305, Q96AN2 |
| UniProt Entry Name | NRF1_HUMAN |
| Gene Symbol | NRF1 |
| GeneID | 4899 |
| NCBI Accession | NP_001035199.1 |
| KEGG | hsa:4899 |
| String | 9606.ENSP00000376924 |
| Molecular Weight | Calculated MW: 54 kDa Observed MW: 70 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |