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Neutrophil Gelatinase Associated Lipocalin / NGAL (LCN2) Antibody (Capture Ab)
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Catalogue No: abx019240
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US$58.00
(Size: 50 µg)
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Datasheet SDS
Lipocalin-2 (LCN2), also known as oncogene 24p3 or NGAL (NGAL), is a protein associated with neutrophil gelatinase. The 25-kD LCN2 protein is believed to bind small lipophilic substances such as bacteria-derived lipopolysaccharide (LPS) and formylpeptides and may function as a modulator of inflammation. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor. NGAL/LCN2 (Capture Ab) is a Mouse Monoclonal antibody against Human NGAL/LCN2. For ELISA and LF immunoassays, it is recommended to use abx019240 (this product) or abx019241 as the capture antibody and abx019242 as the detection antibody.
Research Articles on Neutrophil Gelatinase Associated Lipocalin / NGAL (LCN2)
| Target | Neutrophil Gelatinase Associated Lipocalin / NGAL (LCN2) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, LF |
| Host | Mouse |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant human NAGL. |
| Isotype | IgG1 |
| Form | Liquid |
| Purity | > 95% (HPLC and SDS-PAGE) |
| Purification | Purified by Protein A or Protein G. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P80188 (UniProt, ExPASy) B2ZDQ1 (UniProt, ExPASy) |
| Gene Symbol | LCN2 |
| GeneID | 3934 |
| OMIM | 600181 |
| HGNC | 6526 |
| Ensembl | ENSG00000148346 |
| Buffer | 0.01 M PBS (pH 7.4). Does not contain preservatives. |
| Specificity | It specifically recognize the human NGAL. |
| Concentration | 8.94 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |