Nucleoside Diphosphate Kinase A (NME1) Antibody

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Target	Nucleoside Diphosphate Kinase A (NME1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 29-57 amino acids from the Central region of human NME1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P15531 (UniProt, ExPASy)
UniProt Secondary AC	Q6FGK3, Q86XQ2, Q9UDJ6
UniProt Entry Name	NDKA_HUMAN
NCBI Accession	NP_000260.1 NP_937818.1
KEGG	hsa:4830
String	9606.ENSP00000337060
Molecular Weight	Calculated MW: 17.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Nucleoside Diphosphate Kinase A (NME1)

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