Platelet Basic Protein (PBP) Antibody

PBP binds ATP, opioids and phosphatidylethanolamine, exhibiting a lower affinity for phosphatidylinositol and phosphatidylcholine. This serine protease inhibitor inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PBP contains hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.

Target	Platelet Basic Protein (PBP)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PBP.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30086 (UniProt, ExPASy)
UniProt Secondary AC	B2R4S1
UniProt Entry Name	PEBP1_HUMAN
KEGG	hsa:5037
String	9606.ENSP00000261313
Molecular Weight	Calculated MW: 21.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Monkey PEBP1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Platelet Basic Protein (PBP)

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