Programmed Cell Death 6-Interacting Protein (PDCD6IP) Antibody
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Catalogue No: abx031319
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Research Articles on Programmed Cell Death 6-Interacting Protein (PDCD6IP)
| Target | Programmed Cell Death 6-Interacting Protein (PDCD6IP) |
| Research Area | Apoptosis |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 541-570 amino acids from the Central region of human PDCD6IP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q8WUM4 (UniProt, ExPASy) |
| UniProt Secondary AC | C5MQH7, E9PFU1, Q6NUS1, Q9BX86, Q9NUN0, Q9P2H2, Q9UKL5 |
| UniProt Entry Name | PDC6I_HUMAN |
| Gene Symbol | PDCD6IP |
| GeneID | 10015 |
| OMIM | 608074 |
| HGNC | 8766 |
| KEGG | hsa:10015 |
| Ensembl | ENSG00000170248 |
| String | 9606.ENSP00000411825 |
| Molecular Weight | Calculated MW: 96 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |