Prohibitin (PHB) Antibody
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Catalogue No: abx011383
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Research Articles on Prohibitin (PHB)
| Target | Prohibitin (PHB) |
| Research Area | Tumor Immunity, Hormone Metabolism, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse, Rat, Monkey |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PHB expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35232 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DY47, Q4VBQ0 |
| UniProt Entry Name | PHB_HUMAN |
| GeneID | 5245 |
| KEGG | hsa:5245 |
| String | 9606.ENSP00000479488 |
| Molecular Weight | 30 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |