Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha Isoform (PIK3CA) Antibody
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Catalogue No: abx011338
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US$427.75
(Size: 100 µl)
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Datasheet SDS
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns (4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
Research Articles on Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha Isoform (PIK3CA)
| Target | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha Isoform (PIK3CA) |
| Research Area | Enzymes and Kinases |
| Clonality | Monoclonal |
| Clone | T221 |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PIK3CA expressed in E. coli. |
| Isotype | IgG2a |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P42336 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14CW1, Q99762 |
| UniProt Entry Name | PK3CA_HUMAN |
| Gene Symbol | PIK3CA |
| GeneID | 5290 |
| OMIM | 114480 |
| HGNC | 8975 |
| KEGG | hsa:5290 |
| Ensembl | ENSG00000121879 |
| String | 9606.ENSP00000263967 |
| Molecular Weight | 124 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Specificity | Cross-reacts with Mouse, Rat and Rabbit PIK3CA in IHC-P. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |