Protein Kinase C Epsilon Type (PRKCE) Antibody
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Catalogue No: abx033117
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Protein kinase C (PKC) is a family of serine and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC epsilon is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS) mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.
Research Articles on Protein Kinase C Epsilon Type (PRKCE)
| Target | Protein Kinase C Epsilon Type (PRKCE) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 206-236 amino acids from the N-terminal region of human PKC epsilon. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q02156 (UniProt, ExPASy) |
| UniProt Secondary AC | B0LPH7, Q32MQ3, Q53SL4, Q53SM5, Q9UE81 |
| UniProt Entry Name | KPCE_HUMAN |
| NCBI Accession | NP_005391.1 |
| KEGG | hsa:5581 |
| String | 9606.ENSP00000306124 |
| Molecular Weight | Calculated MW: 83.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |