Pyruvate Kinase, Liver And RBC (PKLR) Antibody
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Catalogue No: abx033142
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US$326.25
(Size: 80 µl)
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Datasheet SDS
PKLR is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).
Research Articles on Pyruvate Kinase, Liver And RBC (PKLR)
| Target | Pyruvate Kinase, Liver And RBC (PKLR) |
| Research Area | Enzymes and Kinases, Metabolic Pathways |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 521-551 amino acids from the C-terminal region of human PKLR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P30613 (UniProt, ExPASy) |
| UniProt Secondary AC | O75758, P11973 |
| UniProt Entry Name | KPYR_HUMAN |
| KEGG | hsa:5313 |
| String | 9606.ENSP00000339933 |
| Molecular Weight | Calculated MW: 61.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat PKLR. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |