Proteasome Subunit Alpha Type 5 (PSMA5) Antibody
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Catalogue No: abx025406
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
Research Articles on Proteasome Subunit Alpha Type 5 (PSMA5)
| Target | Proteasome Subunit Alpha Type 5 (PSMA5) |
| Research Area | Enzymes and Kinases |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/25, IF/ICC: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified His-tagged Human PSMA5 protein (Fragment) |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P28066 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R8F6, B4E2V4, Q3T1C1, Q6IBF7 |
| UniProt Entry Name | PSA5_HUMAN |
| KEGG | hsa:5686 |
| String | 9606.ENSP00000271308 |
| Molecular Weight | Calculated MW: 26.4 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow PSMA5. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |