Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody
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Catalogue No: abx026318
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Research Articles on Prostaglandin G/H Synthase 2 / COX-2 (PTGS2)
| Target | Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) |
| Research Area | Enzymes and Kinases, Tumor Immunity, Infection Immunity, Reproductive Science, Pulmonology, Gastroenterology, Hormone Metabolism, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 363-391 amino acids from the Central region of human PTGS2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35354 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K802, Q16876 |
| UniProt Entry Name | PGH2_HUMAN |
| Gene Symbol | PTGS2 |
| KEGG | hsa:5743 |
| String | 9606.ENSP00000356438 |
| Molecular Weight | Calculated MW: 69 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |