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SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC) Antibody
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Catalogue No: abx034619
Price:
US$333.50
(Size: 80 µl)
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This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Research Articles on SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC)
| Target | SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase (SRC) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/50, IF/ICC: 1/50, FCM: 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human SRC. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12931 (UniProt, ExPASy) |
| UniProt Secondary AC | E1P5V4, Q76P87, Q86VB9, Q9H5A8 |
| Molecular Weight | Calculated MW: 59.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse SRC. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |