Sterol Regulatory Element-Binding Protein Cleavage-Activating Protein (SCAP) Antibody
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Catalogue No: abx026709
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
Research Articles on Sterol Regulatory Element-Binding Protein Cleavage-Activating Protein (SCAP)
| Target | Sterol Regulatory Element-Binding Protein Cleavage-Activating Protein (SCAP) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 54-83 amino acids from the N-terminal region of human SCAP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q12770 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8N2E0, Q8WUA1 |
| UniProt Entry Name | SCAP_HUMAN |
| KEGG | hsa:22937 |
| String | 9606.ENSP00000265565 |
| Molecular Weight | Calculated MW: 140 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |