Signal Transducer And Activator of Transcription 6 (STAT6) Antibody
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Catalogue No: abx016003
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US$427.75
(Size: 100 µl)
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Datasheet SDS
Signal Transducer And Activator of Transcription 6 (STAT6) Antibody is a Mouse monoclonal against Signal Transducer And Activator of Transcription 6 (STAT6). STAT6 protein is a transcription factor activated by cytokines, particularly IL4 and IL13, and is critically involved in the Th2-mediated immune response. STAT6 deficiency results in loss of IL4 regulated functions such as Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL4-mediated cell proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes and in the colon, intestines, ovaries, prostate, thymus, spleen, kidneys, liver, lungs and placenta.
Research Articles on Signal Transducer And Activator of Transcription 6 (STAT6)
| Target | Signal Transducer And Activator of Transcription 6 (STAT6) |
| Research Area | Signal Transduction, Infection Immunity |
| Clonality | Monoclonal |
| Clone | F909 |
| Reactivity | Human, Mouse, Rat, Monkey |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of Human STAT6 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P42226 (UniProt, ExPASy) |
| UniProt Entry Name | STAT6_HUMAN |
| Gene Symbol | STAT6 |
| GeneID | 6778 |
| KEGG | has:6778 |
| Molecular Weight | 94 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |