T-Cell Leukemia/lymphoma Protein 1A (TCL1A) Antibody
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Catalogue No: abx000786
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US$217.50
(Size: 20 µl)
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Datasheet SDS
TCL1A Antibody is a Rabbit Polyclonal antibody against TCL1A. Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements. In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730).
Research Articles on T-Cell Leukemia/lymphoma Protein 1A (TCL1A)
| Target | T-Cell Leukemia/lymphoma Protein 1A (TCL1A) |
| Research Area | Tumor Immunity, Hematology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to TCL1A. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P56279 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6IBK7 |
| UniProt Entry Name | TCL1A_HUMAN |
| Gene Symbol | TCL1A |
| GeneID | 8115 |
| NCBI Accession | NP_001092195.1 |
| KEGG | hsa:8115 |
| String | 9606.ENSP00000385036 |
| Molecular Weight | Calculated MW: 13 kDa Observed MW: 16 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |