Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B) Antibody

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Catalogue No: abx011830
Price: US$427.75
(Size: 100 µl)

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Western blot analysis using TNFRSF11B antibody against HEK293 (1) and TNFRSF11B (AA: 22-401) -hIgGFc transfected HEK293 (2) cell lysate.
Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B) Antibody Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B) Antibody Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B) Antibody

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Datasheet SDS
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Target Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B)
Research Area Cytokines, Metabolic Pathways, Bone Metabolism
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, IF/ICC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human TNFRSF11B expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Shelf Life 12 months.
UniProt Primary AC O00300 (UniProt, ExPASy)
UniProt Secondary AC B2R9A8, O60236, Q53FX6, Q9UHP4
UniProt Entry Name TR11B_HUMAN
Gene Symbol TNFRSF11B
GeneID 4982
OMIM 239000
HGNC 11909
KEGG hsa:4982
Ensembl ENSG00000164761
String 9606.ENSP00000297350
Molecular Weight 60 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 11B (TNFRSF11B)


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